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Treatment Guide · Skin Boosters

Rejuran

Rejuran (Healer) · リジュラン

A skin booster that injects salmon-derived PN (polynucleotides) into the dermis to promote cell regeneration and collagen production.

Time neededFirst visit: 1 hour+ (including numbing) / follow-up: 1 hour. Injections take 5–10 minutes
Anesthesia & PainPlenty of numbing cream, plus nerve block if needed. No sedation. If you're sensitive to pain, try Datena Rejuran (painless)
DowntimeMild (redness and swelling usually improve within 1–3 days; some bruising may last longer)
SessionsFirst course: at least 3 sessions, one month apart
Interval1 month
MaintenanceTop up every 6 months to 1 year, or when dryness returns
Last bookable timeFirst visit 11:30 / 18:30 · Follow-up 11:30 / 18:30

What is it?

PN extracted and purified from salmon DNA is injected into the dermis, where it stimulates the repair response of damaged tissue, supports fibroblast activity and encourages collagen and elastin production. This leads to a stronger skin barrier, better hydration and fewer fine lines.

Who it's for

Improves fine lines, inner dryness, loss of firmness, pores and redness. Formulas made specifically for certain areas, like around the eyes, are also available.

At Datena

  • Rejuran 2cc = butterfly zone / 4cc = full face / Rejuran Eye 1cc = under-eyes, 2cc = under-eyes + eye area / Datena Rejuran 3cc = full face (Rejuran Healer 2cc + Water Glow + numbing agent, painless)
  • You'll receive an authenticity certificate (NFC); if it won't scan, use the QR code on the back for a 1:1 inquiry

Good to know

Redness, swelling, bruising and itching at injection sites are common; they usually appear within 24–48 hours and fade within 3–7 days. Nodules have rarely been reported.

Results and recovery time vary depending on your skin. Pricing and the exact number of sessions will be explained during your consultation after diagnosis. Written based on in-clinic materials as of October 2026.

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